DPCstruct | MC3756

Metacluster Properties and Pfam Annotations

Number of structural domains289
Mean domain length (aa)230 ± 40 aa
Standard deviation of domain lengths39.62
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score84.02
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.47
Mean intra-cluster local Distance Difference Test score0.45
Mean intra-cluster sequence similarity (%)16.36
Pfam Score46.94
Assigned Pfam label(s) PF15753- CL0123- PF05630- PF06101- CL0004

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
R1IKP2 135-300 None
A0A1H9RBY5 36-231 None
A0A842VZX3 12-195 None
A0A2R6L6Z4 30-201 None
A0A815QBV8 48-267 None
A0A2E8RZ40 549-744 None
A0A2E7ZV79 225-405 None
A0A4U1J7X8 42-255 None
A0A0P4W0D0 28-289 None
A0A1F9YYT1 292-504 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.