DPCstruct | MC3756

Metacluster Properties and Pfam Annotations

Number of structural domains289
Mean domain length (aa)230 ± 40 aa
Standard deviation of domain lengths39.62
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score84.02
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.47
Mean intra-cluster local Distance Difference Test score0.45
Mean intra-cluster sequence similarity (%)16.36
Pfam Score46.94
Assigned Pfam label(s) PF15753- CL0123- PF05630- PF06101- CL0004

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
G4Z8U2 700-892 None
A0A1S8LIZ4 134-389 None
W3A5C4 1-232 None
A0A3M1SSI0 8-329 None
H0EVI9 10-241 None
A0A7C9DV55 1-231 None
A0A7W1H800 177-374 None
A0A2H2ZLE0 27-250 None
A0A1V2LRU4 1-280 None
A0A1S1MYQ8 5-220 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.