DPCstruct | MC37541

Metacluster Properties and Pfam Annotations

Number of structural domains52
Mean domain length (aa)99 ± 15 aa
Standard deviation of domain lengths15.38
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score83.22
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)31.23
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
I1CK90 14-116 QTRFERFVKGLKMDGFEVFGYARKSPHKLSSEALKKNLQNMITCLRHRSLVEAVYVSPNSLAKSPIVSRDMSNTDEELVQMELDNCA…
A0A1X2GDH8 209-303 WPNHKQRIQQLKDDGYLIVGYARKSPGGSNAGRVVCLESMTSLLKDRSLVDKVFASHVCRASDRLSGRDMTATTSQSFQGSDGTSQG…
I1CUT8 31-102 None
A0A1X2GQ41 2-110 None
A0A1X2GSS3 19-100 None
A0A1X2GTS1 67-143 None
A0A1C7N9M5 6-94 None
A0A1X2I156 7-92 None
A0A1X2I899 66-166 None
I1CRW2 160-258 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.