DPCstruct | MC375

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)195 ± 34 aa
Standard deviation of domain lengths33.83
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score86.63
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)23.61
Pfam Score90.00
Assigned Pfam label(s) PF03887- CL0057

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0F5JQ90 13-183 NIMEDIITLTAKERLSYALQLRILEKLSPDDDTLKNLKTAIEEGYTIHYQDLFEILSNELSLEDCRFVLDVLEMYRGLIFSALQINE…
A0A2V9PXB0 44-238 HTPVSDGCKEQTGDPPRCVMKLSDGEKLILMVLADMYKHLEIKGEFDPDFISTTISGGHLWGLRWKYTHIPFEKSENPPEVSETVDI…
A0A5C8Z686 1-292 None
A0A6I8MHL5 18-212 None
A0A6N8U514 6-186 None
A0A4Y7AHN2 122-327 None
A0A1B1N395 1-184 None
A0A1E3Z8I3 1-235 None
A0A807CB56 22-185 None
A0A290TE02 11-231 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.