DPCstruct | MC37459

Metacluster Properties and Pfam Annotations

Number of structural domains381
Mean domain length (aa)211 ± 49 aa
Standard deviation of domain lengths49.14
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score86.98
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)16.83
Pfam Score96.17
Assigned Pfam label(s) PF02661- CL0123- CL0105- PF13776- PF13784

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
C6DCV9 19-194 VLINKLGINDDSQFDDAERQLSELAVLDIEFEEPPYDLHYWCGLHGKIFGDLFDWAGEIRRIDISKGQTRFCTVSRIEIEANKIFMQ…
A0A496I0G9 34-229 LAETISILTTEYIPREMPQRAFFEVKNYQNMLFFLLENLNKRQSVDSFFIRELHGILMNFLLPNKEVFKTTDNTILGASFETTPHFQ…
A0A847VFZ2 511-691 None
A0A7H8YYN6 338-560 None
M3UFK0 57-247 None
H2J000 40-305 None
A0A2T0PWV3 2-208 None
A0A535A7B5 134-394 None
A0A1V5GDN9 74-341 None
A0A3M1TKH2 22-207 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.