DPCstruct | MC37426

Metacluster Properties and Pfam Annotations

Number of structural domains279
Mean domain length (aa)188 ± 30 aa
Standard deviation of domain lengths30.06
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score86.38
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)19.85
Pfam Score83.68
Assigned Pfam label(s) CL0123- CL0174- CL0388- CL0036

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5P3A0P6 6-191 DPGQRLDEQLLGNRFNVSRTPVREALRLLAANGLVTLEPRLGAIVSRPTVSEIFDLFELVGEMEASAARLACERMTPDSRNRIADTH…
A0A645HDA8 2-131 AMLEGECARSSASRASDKDLDSLRHIHEDLEHAASKRDIDAFFEANQAFHHALQQLADNRWLLHVIEDLRKVIKLSRHHSLFSEGRL…
A0A4R2JZD6 19-223 None
A0A259KA57 42-249 None
A0A485JMU6 6-177 None
A0A6N2DRL8 166-395 None
A0A850R2V9 7-132 None
S9S327 353-565 None
A0A377BYF1 9-203 None
A0A1V5USD5 19-223 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.