DPCstruct | MC37407

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)144 ± 13 aa
Standard deviation of domain lengths12.83
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score94.69
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.89
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)45.21
Pfam Score75.00
Assigned Pfam label(s) CL0193- CL0061- PF14805

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6M1HZ49 1-126 ITPANVDTVTREAVNQVIGLLDSGALRVAEKIDGQWVTHQWLKKAVLLSFRINDNKVMDGAETRYYDKVPMKFADYDEARFQKEGFR…
A0A848EMH5 19-148 ETLKKRVTSLHQGNAKLQDQELRSLLSEFIYALEKGGVRAAEDAQGEWRSNQWVKQGILSLFKHCKNSRQGKHGTSSDVLPTRSIEN…
A0A1Y0D1G3 3-125 None
A0A6A5LCB9 3-155 None
A0A6A5L6U4 4-148 None
A0A4Q5ZQC7 8-134 None
A0A357NRD9 79-233 None
A0A7J7AGT0 389-555 None
A0A6L5DK67 445-594 None
A0A7R8WVR1 1-143 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.