DPCstruct | MC37302

Metacluster Properties and Pfam Annotations

Number of structural domains497
Mean domain length (aa)276 ± 54 aa
Standard deviation of domain lengths54.00
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score86.41
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)20.11
Pfam Score96.98
Assigned Pfam label(s) PF12142- CL0205- PF01161- PF14830

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2L2XEG7 2-172 ARPSLNDLNENDRALLAEEIQRYVTPDIVDIHWNAVLSGAHNDPAMFLSFHRDYISGLENFLSDRGYTQFVPLPAWNPKNPIPEEFN…
A0A010RYF3 443-726 VSGTIALPVQDAPLRVEWRSLSSAAKADYISAVKCLDGLPSKIGLETSRYNDFPYVHAQLNNEIHFVAQFLPWHRYFVHIYETALRD…
A0A1S8VG51 7-199 None
A0A7R9PVW4 525-816 None
A0A1X6PJ49 348-643 None
A0A0F7RVY0 296-620 None
A0A6P8I080 46-313 None
A0A7M5U0C1 259-570 None
A0A6P8IFD5 272-534 None
A0A2G8L6J4 527-768 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.