DPCstruct | MC37294

Metacluster Properties and Pfam Annotations

Number of structural domains31
Mean domain length (aa)314 ± 61 aa
Standard deviation of domain lengths61.49
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score77.43
Mean fraction of residues predicted as intrinsically disordered0.32
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)23.72
Pfam Score95.83
Assigned Pfam label(s) CL0020- CL0186

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7S1T5R3 1-349 HNFNSVEEAGAWGDEDLEIDGVEVVDTQPVDQQDEFGNERSEDVVEGGYYVAPMPGPGRLVRWTRNAALAGELAAAGAVEEAMKLLS…
A0A1S3I493 164-367 LVQRLQTAYQMTTQGKFAEAVDRFRSILLSVPLLVVDTKQEITEAQQLIEICREYIVGLSMELKRKEMPKENLEQQKRLCEMAAYFT…
L8HEI2 59-472 None
A0A7F8RQJ6 257-671 None
A0A5J4WKH5 473-813 None
A0A820BYS4 81-504 None
A0A1U8PNE3 72-374 None
A0A498IXR9 37-280 None
M5FZP2 226-478 None
A0A843UBC8 376-688 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.