DPCstruct | MC37285

Metacluster Properties and Pfam Annotations

Number of structural domains1192
Mean domain length (aa)124 ± 20 aa
Standard deviation of domain lengths20.45
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score83.10
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)22.02
Pfam Score94.68
Assigned Pfam label(s) PF20240- CL0161- CL0029- PF12625- CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A449BIW3 3-108 None
A0A6N7Y3Q2 12-126 None
A0A377ZX08 49-188 None
A0A1K1RWM9 342-461 None
A0A6P1D5I0 124-261 None
A0A519KGF2 120-240 None
A0A6N7SB22 238-374 None
A0A5B1BA15 5-101 None
A0A5B8SR33 141-282 None
N8QA54 64-199 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.