DPCstruct | MC37285

Metacluster Properties and Pfam Annotations

Number of structural domains1192
Mean domain length (aa)124 ± 20 aa
Standard deviation of domain lengths20.45
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score83.10
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)22.02
Pfam Score94.68
Assigned Pfam label(s) PF20240- CL0161- CL0029- PF12625- CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Y4U770 1130-1265 None
A0A5C6XVA9 495-629 None
A0A1F8MBL7 24-131 None
A0A349J801 239-349 None
A0A2Z5KDX8 363-483 None
A0A4Y1X6F9 120-301 None
A0A1I3TX22 59-179 None
A0A5C5XCC6 67-180 None
A0A5C0AST1 130-258 None
A0A7W2DPC4 209-342 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.