DPCstruct | MC37285

Metacluster Properties and Pfam Annotations

Number of structural domains1192
Mean domain length (aa)124 ± 20 aa
Standard deviation of domain lengths20.45
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score83.10
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)22.02
Pfam Score94.68
Assigned Pfam label(s) PF20240- CL0161- CL0029- PF12625- CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A831JEE2 23-144 ATSFLEEISDLFAGAKRNENNIVERVVKYINENFEKEIRLKELSQTIYLNPEYFSRLFKKEVGCTYVEYLTRIRIEAAKKYLANPSL…
A0A6N8ZFW3 283-422 DLPVEFTEYLAWRGLRVDRGTCDIIRRTVRLARHLTTIASLSRTIYLSRRALGRRFVSRGLPVPSHWLQFCRILHAVLRLQNSSQSL…
A0A160UFH5 177-317 None
A0A3B0C3T5 402-529 None
A0A7I0EF37 1-122 None
A0A251WNU6 3-154 None
A0A424L368 8-118 None
A0A191ZSH2 125-249 None
A0A1Y4HBV3 124-251 None
A0A557R2S6 78-185 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.