DPCstruct | MC3728

Metacluster Properties and Pfam Annotations

Number of structural domains19
Mean domain length (aa)116 ± 10 aa
Standard deviation of domain lengths9.96
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score85.04
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.79
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)21.45
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1E5L2F4 245-355 DFIKNNLKIGLLPADVENLLENNFTIVYAALDGQEMWRYDIFTIEDYVLENEYQTDSVDLDGILEGEISIQLFVGFDNDKKVSRYII…
A0A1D8JED4 2-105 MKNAKEGLSAKEVKEVFGEPLLSDTVDSTETWLYSTPADDTDYKPSLEAVNHQAILDEVVDYELYINFLDNKAYIYSYFYKSGEDVR…
A0A161RX33 5-107 None
A0A0A5G4N2 79-202 None
A0A1I4LP66 289-408 None
A0A7Z2VPV4 71-209 None
I0BN20 419-547 None
A0A2I0QS10 82-195 None
K1KU10 22-140 None
A0A4S4C3D9 1-103 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.