DPCstruct | MC37263

Metacluster Properties and Pfam Annotations

Number of structural domains684
Mean domain length (aa)122 ± 23 aa
Standard deviation of domain lengths23.10
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score82.21
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)14.10
Pfam Score95.72
Assigned Pfam label(s) CL0092- PF08069- CL0472- PF04815- CL0128

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4W3HI38 8-108 IARSLQSSAGVRIWRIEKMEMEPVPQASYGNFYEGDCYIVLATRKIARSLCHDVYFWLGRQSSQDEQGAAAIYTTQIDDALQGAAVQ…
A0A1J4KDH9 4-126 VSAPEIKEAYDEIRSEKETDWVFVKPSDGNPNKWVLHAKGSDGVAGLAASLDESILGYGYLRVKDGAGRTKFIFLQYVGPNAKRTVS…
A0A6J1X2W8 18-128 None
A0A1X2IFE0 7-130 None
A0A5B7BTV7 176-302 None
A0A553N2G8 417-549 None
A0A821QV75 7-112 None
A0A5P1EV69 50-142 None
A0A1Z5SAI4 71-155 None
A0A1I8IK45 611-758 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.