DPCstruct | MC37257

Metacluster Properties and Pfam Annotations

Number of structural domains44
Mean domain length (aa)219 ± 29 aa
Standard deviation of domain lengths28.58
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score80.57
Mean fraction of residues predicted as intrinsically disordered0.32
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)27.72
Pfam Score96.15
Assigned Pfam label(s) CL0012- CL0465- CL0126

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5B6VQ05 12-203 NGQVTFLVTIGVFTVVILVLWRTVLLLPFKLITVFLHEASHAIACKLTCGHVEGIKVHADEGGVTQTRGGIYWVILPAGYLGSSFWG…
A0A427YIL6 27-274 TFQTNTIIAACVMFIAILIAWNLPILRDIIAALKLFVVGIHEMCHLAVGLMCGGQIVSICIDPNDGGATHIMNLMRTFPRVPRDPYA…
A0A2U3ELT5 830-1076 None
A0A7V4GHG3 69-298 None
E6RG65 29-222 None
R7W5L9 14-265 None
A0A6B1E015 108-345 None
A0A6L6CH80 37-262 None
A0A6A2YQ61 3-192 None
A0A834ZMF3 93-323 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.