DPCstruct | MC37254

Metacluster Properties and Pfam Annotations

Number of structural domains54
Mean domain length (aa)151 ± 23 aa
Standard deviation of domain lengths23.10
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score83.67
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)37.38
Pfam Score98.68
Assigned Pfam label(s) CL0125- PF00368

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5B6VBT4 2-139 ACSPSIVDHIIPTVSSAEDEEMVDLVVKGTIHSHALEEQVGDCKGAVRIRREALQRITRRSLQGLPLDGFDYGSILKQCCEMPVGYV…
Q2HEP4 3-107 DFTRAVKIRRTIISRTKATADLTGVLERSKLPYQGYNWAQVHGACCENVIGYMPLPVGVAGPLVIDGQSYFIPMATTEGVLVASTSR…
A0A0V1A4Q6 264-420 None
A0A453PE64 69-229 None
A0A446XCL6 115-260 None
A0A5N6G5Q8 303-471 None
A0A6A2XYC0 145-274 None
A0A654I117 288-434 None
A0A1Y2HJ60 434-582 None
A0A0P7GMD0 5-132 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.