DPCstruct | MC372

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)192 ± 20 aa
Standard deviation of domain lengths20.27
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score85.84
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)17.94
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A109K5K6 1-173 MLSERQFLFLREAALQLQYALDAFEEFARLKQSSARPDTLFKALDDFLDHAARVEAVFWPTKKYFARGQELRELLSVKDDNYLHNHE…
A0A2V9PJ59 1-174 MQRLDWMFLMELQRQCRFTLLAASEIHNAMHESDGTRKPTDMTQFWYNIQGLLGAVGNVSKILWPPAKRCQPRGSRLRALLSVADTS…
A0A1W6DLU4 27-245 None
A0A837GFH2 4-177 None
A0A7W5ATB9 7-207 None
A0A1H9EAV7 59-257 None
F2IUL1 15-195 None
A0A4R3RTZ0 1-205 None
A0A1Y4R447 13-205 None
A0A5A7MTZ4 1-207 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.