DPCstruct | MC3705

Metacluster Properties and Pfam Annotations

Number of structural domains1315
Mean domain length (aa)237 ± 58 aa
Standard deviation of domain lengths57.82
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score87.90
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.42
Mean intra-cluster sequence similarity (%)13.60
Pfam Score79.83
Assigned Pfam label(s) CL0022- PF07005- CL0015- PF06140- CL0396

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A849WTX1 116-360 None
I1CV42 157-446 None
A0A445CSI2 154-385 None
G2YIG2 68-363 None
M4CPY1 155-413 None
A0A3B4AC39 57-298 None
A0A3A4XMB9 497-813 None
A0A838EWT6 7-171 None
A0A2G4E456 1-212 None
A0A0B7NBH8 3-225 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.