DPCstruct | MC3705

Metacluster Properties and Pfam Annotations

Number of structural domains1315
Mean domain length (aa)237 ± 58 aa
Standard deviation of domain lengths57.82
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score87.90
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.42
Mean intra-cluster sequence similarity (%)13.60
Pfam Score79.83
Assigned Pfam label(s) CL0022- PF07005- CL0015- PF06140- CL0396

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
W1F0A6 49-197 LIETQGETAQALAIRLARPVVVVDKMAGKVVTIAAAAVNPDSATRKAIYYLQQQGKTVLQIADYPGMLIWRTVAMIINEALDALQKG…
A0A497JMG7 5-241 SNSLKVCVVGLGNVGHPTASYIHENGYLVYGYDIDPQKTSQINPITAFCEWEKVPECNIYVVCVNTGWKNGKPDMSNVFDACQKIAE…
A0A7R9Q0K2 385-677 None
K9V1H0 1-233 None
A0A446J143 185-397 None
A0A3Q4HAT9 24-280 None
A0A438MX65 19-305 None
A0A0H2M8Z8 1-196 None
F4Q5M4 2-193 None
F4PS83 499-790 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.