DPCstruct | MC37039

Metacluster Properties and Pfam Annotations

Number of structural domains41
Mean domain length (aa)66 ± 6 aa
Standard deviation of domain lengths5.59
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score79.46
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)40.64
Pfam Score65.81
Assigned Pfam label(s) CL0229- PF12451

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A453BV02 15-78 MKREIEDLKTNAKVFQLSKCTACTFTLDLPAVHFMCMHSFHLRCLGDNEKECPECAPEYRSVME
A0A822Y836 1-63 MRKEIQDLRTNARIFQLSMCTACTFTLDLPAVHFMCMHSFHQHCLGDNEKECPECAPEYRSVL
A0A0G4KT86 469-534 None
A0A0D8X9D6 1-57 None
A0A397F5D7 346-408 None
J4UDN5 912-977 None
A0A0R3UQS1 29-91 None
A0A2W1BS46 559-625 None
A0A0B1TKF4 35-92 None
A0A0C2JHD5 53-131 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.