DPCstruct | MC36974

Metacluster Properties and Pfam Annotations

Number of structural domains368
Mean domain length (aa)107 ± 16 aa
Standard deviation of domain lengths15.99
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score86.73
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)28.74
Pfam Score91.24
Assigned Pfam label(s) CL0123- CL0263- PF18755- CL0167- PF00832

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A376EI35 24-122 None
A0A0U3NEF0 50-180 None
A0A2R5G6K5 227-344 None
A0A2M6YS78 5-130 None
A0A6B0PZU0 348-454 None
A0A2T5I9M1 20-130 None
A0A6C1LS37 58-166 None
A0A6N7Z0D0 234-349 None
A0A355UQA9 4-95 None
A0A1V4KHU3 133-254 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.