DPCstruct | MC36974

Metacluster Properties and Pfam Annotations

Number of structural domains368
Mean domain length (aa)107 ± 16 aa
Standard deviation of domain lengths15.99
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score86.73
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)28.74
Pfam Score91.24
Assigned Pfam label(s) CL0123- CL0263- PF18755- CL0167- PF00832

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A497FUB7 50-170 VPTPMLIYSIVKNIPRGKLITDKLLREKLAEKYGADFTCPLATGWFIRIVAEYSEEEIKSGKKLSEVAPYWRILRSNGSLYEKFPGG…
A0A564TWC2 54-153 DLVTDSPTKRIYEAVKQILKGHVATYRQVAKMAGNEKMSRAVGNALHKNPDPEHIPCFRVVNAKGELAGAFAFGGANVQAELLREDG…
A0A538QJH9 11-112 None
A0A1X0UKJ1 28-116 None
A0A430B0E1 48-160 None
A0A7R9L3Q8 215-309 None
A0A7R9KNZ6 296-415 None
A0A5R9PGL8 282-395 None
A0A2E9Y6K4 16-122 None
A0A5S5DTA0 109-201 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.