DPCstruct | MC36972

Metacluster Properties and Pfam Annotations

Number of structural domains128
Mean domain length (aa)148 ± 28 aa
Standard deviation of domain lengths28.45
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score86.34
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)32.81
Pfam Score76.45
Assigned Pfam label(s) CL0031- PF12368

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
K2C169 15-148 MDYYEQFKDKKIVMYCTRGVRCESATALFVQYGFDKKNVYHLEGGIVKYAEKYGNEGFFEGKCFTFDDRIALVVNTSDTAVILGNCA…
A0A1E3GU86 1-112 MFCTGGIRCEKSTAYLKEQGFEEVYHLEGGILKYLEDVPEQESLWEGECFVFDERVTVNHSLEKGEYDQCHACRLPITEEDKQSEKY…
A0A5B6YM78 43-212 None
A0A1R3KN60 87-238 None
A0A812NLV7 408-547 None
A0A3L7PDC7 148-269 None
A0A4P9Y0Z8 173-319 None
A0A7S3FTL5 162-321 None
C1N3F0 362-508 None
A0A2N9GKS0 204-341 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.