DPCstruct | MC36969

Metacluster Properties and Pfam Annotations

Number of structural domains59
Mean domain length (aa)143 ± 26 aa
Standard deviation of domain lengths25.85
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score79.59
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)44.28
Pfam Score98.72
Assigned Pfam label(s) PF03759- PF00504

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A453Q4D6 18-170 MWNREMDCLLSICEYIVEFAPTVQARPDGSTHDVMATSPRSDILMNLPALEKLETMLLGILDSFDKAEFWYADQRKQSFTETKKPSS…
A0A3P5YR46 1-100 MTPKPRADIHMNLPALRKLDSMLIETLDSMVNTEFWYSEVGPRAEESRRWWLPSPKVPKPGLSSLVRKNLLEKGNVVYQSFKAAKSI…
A0A1D6PWZ1 118-220 None
A0A830C305 43-195 None
A0A0E0JR22 70-271 None
A0A835RGH6 138-290 None
A0A445DD76 196-360 None
A0A446Q002 43-191 None
A0A5D2TNM5 232-385 None
A0A5P1ET14 178-363 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.