DPCstruct | MC36900

Metacluster Properties and Pfam Annotations

Number of structural domains127
Mean domain length (aa)144 ± 35 aa
Standard deviation of domain lengths34.77
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score87.61
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.63
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)18.98
Pfam Score81.35
Assigned Pfam label(s) CL0209- CL0369- CL0036

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7R8GYY3 743-866 ESWNYWDAVSSLGVFIDSEGHLKLDTIKVFARPYPQATNGVPKFLKYDPFTGDFNYRFLAKDSMNQVPTEIVIPKFAYENYKYKVTL…
L8HC21 1-79 MNFDPETGVFQLTYILNLKVSQPTEIYLNEEYYYANGYVVSVVPSQIVQAKSPGKNLVWVYALPTATDGATITVTISPK
A0A0S4JNZ0 275-374 None
A0A498PFB8 10-185 None
A0A183MAN9 34-192 None
A0A0B7NAD8 515-693 None
A0A522UEV2 2-117 None
A0A1V6HQM6 351-495 None
D0MUI9 25-142 None
A0A1V6HC21 547-674 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.