DPCstruct | MC36779

Metacluster Properties and Pfam Annotations

Number of structural domains17
Mean domain length (aa)120 ± 12 aa
Standard deviation of domain lengths11.94
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score72.51
Mean fraction of residues predicted as intrinsically disordered0.36
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)35.73
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A1Z971 1-109 MPCESCGVEFTVFRRKRACFDCKRYYCANCIASRRCKRCSVFAQRPLSRTDLLKLKPKDLIFYLQSKHISTEGCLEKEELVGLVLTH…
A0A6P8ZGL9 25-145 VCEICGTKLSVFRKKKPCLECKKQFCSQCLLRGRDRTLHCKNCYILCMRPPLRSALLNLRIKDLQHYLNQHNVSTRGCLEKEDLVNV…
A0A182FFU6 32-142 None
A0A2I0TV45 4-125 None
A0A819TVS1 11-138 None
A0A1A9X3Q0 368-490 None
A0A182MQZ2 1-116 None
A0A1A9USS2 1-123 None
A0A286XXA7 1-105 None
A0A3B3QPV0 61-189 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.