DPCstruct | MC36774

Metacluster Properties and Pfam Annotations

Number of structural domains46
Mean domain length (aa)105 ± 23 aa
Standard deviation of domain lengths23.16
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score82.22
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.75
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)33.87
Pfam Score100.00
Assigned Pfam label(s) PF10170

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A146MJ75 2-86 SSEIQNELFHCSVCDLKIRYDYKGDKPPFFKKDIKLLESVYCIRDPFADDNLGGIILGGDCSVCRRSVCISQDCSTYNMKRYCIC
A0A1S3INF3 1-94 MTSKFLCSKCGFCINYDYFGNKPPGADTLLLLEEAYIMNDPFAENRRGKFIILGSHCSVCSKSVCIAQGCSIFYTKRFCIDCVIKNL…
Q8R3A2 2-101 None
A0A556THD0 1-74 None
A0A7N4NNP8 506-598 None
A0A7N4NZX8 130-222 None
A0A835NW08 69-166 None
A0A834AVY9 51-153 None
A0A061RIH7 1-93 None
A0A0N5CJS3 12-149 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.