DPCstruct | MC36759

Metacluster Properties and Pfam Annotations

Number of structural domains200
Mean domain length (aa)102 ± 15 aa
Standard deviation of domain lengths15.25
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score77.25
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.69
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)25.62
Pfam Score99.52
Assigned Pfam label(s) PF01161- PF01253

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7R9YLU2 32-132 VEVDGFEPRERKGALPPIIISMGRAAGHNKTSVSGLETYHVDPDELARYGKRLFNCTTSVAELPGKYVREKEVTLQGHCVSEMVEHL…
A0A812GKH2 16-97 VVNATKKGGLPIKVESRAKGKKVTIISGVQGDAQSLVSALGSLLGCGGSVCHAAGQTQVLVQGDQTERISGSLEQLGCLRGM
A0A4V3WL97 82-171 None
A0A6I9K736 78-200 None
A0A4U0VPU3 326-423 None
A0A1E5UP09 74-172 None
A0A0F7SUM9 33-150 None
A0A0F7SGV7 741-839 None
A0A7R9L011 117-218 None
A0A183LNU1 69-161 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.