DPCstruct | MC36755

Metacluster Properties and Pfam Annotations

Number of structural domains136
Mean domain length (aa)240 ± 47 aa
Standard deviation of domain lengths46.86
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score72.54
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.55
Mean intra-cluster sequence similarity (%)22.54
Pfam Score88.16
Assigned Pfam label(s) PF04578- CL0184- CL0523- PF13968

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
Q5Z830 43-278 LHKSANVPTQVKAAVLAALKRSNGRLSNGVAAIQRSTLRDTVIWSCQGDHIVTANVILVWHIGTSLFEMKYLRIKSSPRTADMITAT…
N1QXE4 1-155 MKNVSSDEENKLRPHLDVATKLSKYCAYLLVSARKLLPGRPYDTLCVLDAVAVEATVFLKNSRDKYEVMRNLAGSEETIFEGGAKLG…
Q7XS29 38-346 None
A0A2N9I9Z8 40-315 None
A0A4S4DXG3 6-195 None
A0A438DK32 1-213 None
Q7XRV7 682-941 None
A0A6P5MZU5 310-594 None
A0A4U6TG15 12-219 None
M7YL00 751-1029 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.