DPCstruct | MC36726

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)136 ± 12 aa
Standard deviation of domain lengths12.48
Length coefficient of variation0.09
Mean AlphaFold2 pLDDT confidence score76.35
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.59
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)71.76
Pfam Score100.00
Assigned Pfam label(s) PF07095

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A447N2S1 1-139 MKGAQAIEATTVKQLEKAGVRVGDTLHLSGKGMCNIHSGATWSGQSNSPFMPFDCSQIIWNDAPALPLPESDLVNKAMALSQAVNRQ…
A0A378EAJ4 1-108 MRIGDTLRLTGTGMCNIRTPGSWSAKEDSPFLPFDCSQIVWNDAPPLPLPESDIVSKATALMQSVQRQLHPETDDDSRVSPALRSAI…
A0A3S4DVU8 1-117 None
A0A376TWS6 42-181 None
A0A376S1E9 358-497 None
A0A378AKY9 1-161 None
A0A655DLB9 30-169 None
A0A6N8Q9Y5 46-184 None
A0A379FKQ4 1-135 None
A0A2X2WG00 130-269 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.