DPCstruct | MC36634

Metacluster Properties and Pfam Annotations

Number of structural domains324
Mean domain length (aa)125 ± 21 aa
Standard deviation of domain lengths20.58
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score87.43
Mean fraction of residues predicted as intrinsically disordered0.38
Mean length-normalized TM-Score0.56
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)17.04
Pfam Score100.00
Assigned Pfam label(s) CL0084

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A380Q3H2 3-98 VQKASNDLHGLRFHDYGKTARAEGQYLFETFTPQINRNGLALPPDWNGMTGIKQWQITPNTTIIRGRAAPQFEYGSQYSGGADQIFV…
A0A3R6RJE5 20-128 PRVYRKQILESFNVETIKLQTAGDSTYGLRFYGGNANTEGRYLFETFSPLTNRQNLALPYEWNRMTGIQQFQVRSGTIMITGKTAAQ…
A0A521GMW9 8-100 None
A0A521GMU6 107-243 None
A0A3M0Y6J3 281-397 None
A0A378RM51 42-204 None
A0A7K1L5Y1 476-577 None
A0A419HMQ1 812-932 None
A0A419HCW3 545-649 None
A0A1Y3TH61 385-506 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.