DPCstruct | MC36633

Metacluster Properties and Pfam Annotations

Number of structural domains43
Mean domain length (aa)254 ± 33 aa
Standard deviation of domain lengths32.65
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score82.66
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.39
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)15.79
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3R6QSC8 55-295 VEGLEEVKEVDPFEDIEVTFSGTPPYVYPDWTNNSDDDYLRYLWFNFEDYDSLDVGDTVTLTVDESEENALANGYKFTQTSKEYTVS…
A0A352WFR1 259-544 DYISGSLNKDSALTNGDTIKYKWDVDKTKIEKLFKVKVKCSTVEHKVSGLKKVKTKDIKKDLNIKFEGEDGEGYAYFDSDKEYGIYF…
U2SKN4 47-306 None
A0A837IMW6 2-219 None
A0A2P1G4G0 104-360 None
E7FXQ6 180-446 None
A0A5R8QFE5 142-409 None
A0A251WQW1 305-554 None
A0A3B9FZN8 106-408 None
R6UJQ9 79-385 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.