DPCstruct | MC36601

Metacluster Properties and Pfam Annotations

Number of structural domains109
Mean domain length (aa)146 ± 25 aa
Standard deviation of domain lengths24.88
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score84.54
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.75
Mean intra-cluster local Distance Difference Test score0.68
Mean intra-cluster sequence similarity (%)32.41
Pfam Score99.49
Assigned Pfam label(s) CL0123- PF00137

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0X3NPC2 8-138 YFIACGAAYGTARSSMGISCMAVRKPELIMKSLVPIVMAGIIAVYGLVVSVLIAGQVSVDYTLQQSLSHFGAGLSVGLSGLAAGYAI…
A0A0U3FW37 4-153 GLALAIFGAAIAAGLAGIGSAKGVQISGEAAAGVVAERPEMFGKMLVLQALPGTQGIYGFLTAVLIMVQIGILGGTPLDLSLYQGMS…
A0A366R651 13-144 None
A0A396H5I4 102-265 None
A0A662MGV3 90-243 None
A0A653BR05 11-166 None
A0A6A6GMC6 32-195 None
A0A6A3NFK3 10-120 None
A0A7C1CI15 1-175 None
A0A5C3L3T2 12-158 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.