DPCstruct | MC36595

Metacluster Properties and Pfam Annotations

Number of structural domains322
Mean domain length (aa)127 ± 34 aa
Standard deviation of domain lengths34.22
Length coefficient of variation0.27
Mean AlphaFold2 pLDDT confidence score87.40
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)19.41
Pfam Score68.52
Assigned Pfam label(s) CL0649- CL0668- CL0588- CL0271- PF00173

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
E6RDN1 118-248 EALGLTKCHDRISIFTIHSVPIFFQHFDGPFIPTLKLLHMYPDMLPHVQIDRGAIKFLLAGANMMAPGLLSAGGKLPDGMEKDTIVA…
A0A843MCT0 80-221 AIADYQFGVGVGDALFTGNIKIEKSKKTGKIRHIYDGKTLIVNMRASDSFLILSKEGAKRLHAATQYPKNRVVVNKDSEPFSLEGKS…
A0A0B3ABW9 811-893 None
A0A654GRI8 2-81 None
A0A662UVF1 21-178 None
A0A2I3M5T2 9-159 None
A0A6A5E1Z7 303-388 None
A0A6A5D9X3 25-197 None
A0A6V8H002 21-179 None
A0A0F4Z0C3 58-213 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.