DPCstruct | MC36572

Metacluster Properties and Pfam Annotations

Number of structural domains125
Mean domain length (aa)175 ± 25 aa
Standard deviation of domain lengths24.78
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score84.41
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)27.16
Pfam Score76.78
Assigned Pfam label(s) PF04561- CL0410- PF04563- CL0028- PF04565

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A317IUS6 270-450 None
A0A2H1CFZ0 45-281 None
A0A5C7LWI4 130-294 None
A0A7V3NZK5 198-381 None
A0A444U1F6 231-422 None
Q3ZJ93 380-555 None
A0A6C0I2P2 405-599 None
A0A0H1RSS3 113-282 None
A0A3P6BDA0 49-228 None
A0A1R3KJL5 15-188 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.