DPCstruct | MC36572

Metacluster Properties and Pfam Annotations

Number of structural domains125
Mean domain length (aa)175 ± 25 aa
Standard deviation of domain lengths24.78
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score84.41
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)27.16
Pfam Score76.78
Assigned Pfam label(s) PF04561- CL0410- PF04563- CL0028- PF04565

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7J3DL87 19-196 ADRLAKAFYLGMMASKAIETYYNLRQEDDKDHYANKRLELSGKLMEHLFRYAFKYFVKDLKFQIDRTVTRRRKLNINTIVRPDAITE…
W4UJW2 20-172 VVEPDDIDHFGNRRLRTVGELIQNQLRTGLSRMERVVRDRMTTQDIEAITPQTLINIRPVTAAIKEFFGTSQLSQFMDQNNPLAEMT…
A0A6S8SMV0 63-271 None
A0A2G3D3A9 77-224 None
A0A426H4V6 24-207 None
A0A345HH11 224-427 None
A0A2G3BI38 60-256 None
A0A1P8BFS9 314-532 None
Q8HTL6 478-665 None
A0A4S8I2F4 81-266 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.