DPCstruct | MC36527

Metacluster Properties and Pfam Annotations

Number of structural domains60
Mean domain length (aa)125 ± 23 aa
Standard deviation of domain lengths22.93
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score70.26
Mean fraction of residues predicted as intrinsically disordered0.57
Mean length-normalized TM-Score0.45
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)29.23
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A067DAA4 22-167 SSSASPSRCFYTARAYDAAPKPKVNKTCLYRTGKCNNARHVKPNGSLHKMCTYHRSKANENQRRLDQKKKDAGFHRRERISAFKVKG…
G4Z2E3 30-124 PLTATSQPPPPSAASGERGAPVDDMLCRYRNKKCGYPRAIKRNGERHNLCERHRAKANQNQRKLESKRRTQKRMLQQRVAAVDRVVK…
K3W5F6 29-159 None
A0A6G0XWZ3 8-100 None
A0A6G0XGL1 18-161 None
A0A0P1B5M3 14-159 None
A0A0P1AXK6 11-170 None
A0A1V9ZNQ0 159-314 None
A0A1V9ZXK3 11-154 None
K3W7M9 2-142 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.