DPCstruct | MC36504

Metacluster Properties and Pfam Annotations

Number of structural domains42
Mean domain length (aa)118 ± 26 aa
Standard deviation of domain lengths25.90
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score75.60
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)28.16
Pfam Score69.32
Assigned Pfam label(s) PF04678- CL0159- PF20520

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
G1Q8H6 6-115 KLCESLKCYQAHLYSTVAPPDEVTVSYRHGLPLITLTLPSRNERCQFVVKPMLSTVGSFLQDVQNEDKGVKNAAIFTADGSEIATST…
A0A6L5CK83 3-66 YEVTVEYSRGLPVVTVPLPSRRERCRFTLRPISHTVGDFQSMLAREDRGIDRVAVTTMGMSVIK
A0A6A3YN98 3-87 None
A0A3P7I9V6 51-176 None
A0A813SQC0 223-330 None
A0A4U5U8W1 3-144 None
A0A0M3HHD8 2-78 None
A0A834NJZ7 4-99 None
J9A934 47-133 None
E4YK38 294-416 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.