DPCstruct | MC36493

Metacluster Properties and Pfam Annotations

Number of structural domains141
Mean domain length (aa)112 ± 22 aa
Standard deviation of domain lengths21.93
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score80.09
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)39.99
Pfam Score97.28
Assigned Pfam label(s) CL0425- PF18199- PF00177- CL0021- CL0036

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A194PW84 10-113 ILRVAASHYSEEDKIFRDSARPGRRTRMRSGVEAKQPNSAIRKCVRVQLIKNGKKVTAFVPRDGCLNHIEENDEVLVAGFGRKGHAV…
A0A2D3VME9 42-155 QATYNQVLRGCRVEQRARKPTSPALVNRPEMKGVCLRVGTTKPKKPNSGERKVARVRLSSGRVITAYIPGEGHNVQQHSVVLVRGGR…
A0A5D2L9X8 25-109 None
A0A0D8XN65 5-85 None
A0A1R3L0S9 4-113 None
A0A445CQA9 7-101 None
A0A1B6Q9Z8 2-68 None
A0A154PJF7 474-578 None
A0A6P8CZN8 229-359 None
I7I7W8 47-163 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.