DPCstruct | MC36449

Metacluster Properties and Pfam Annotations

Number of structural domains37
Mean domain length (aa)270 ± 52 aa
Standard deviation of domain lengths51.92
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score79.06
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)17.74
Pfam Score100.00
Assigned Pfam label(s) PF07163

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Q2DF32 36-278 PPAATNGSPSTSAAPLRSLYTRAARAFLHRDIRLTYSLIESAFQLLRPPVLVHDALLEHRRKWDILRITLETTIYSDPPSIESLPES…
A0A2V1A6H5 11-250 QSVILNDYKLAVKFFMNKDFEKSYQIISKLHSVAYRTFAKGAISEDVFVKIVTLYLTELGLLLNSKDGTFQLPRKEKKELIGKLRSS…
A0A1E3QLS0 4-379 None
A0A2T0FG48 30-320 None
A0A4R0R5P0 11-287 None
A0A177WSZ5 9-296 None
A0A395IJR3 10-244 None
A0A1E4SYJ8 31-441 None
D8QQK7 9-243 None
A0A6M7YMH1 1-349 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.