DPCstruct | MC36440

Metacluster Properties and Pfam Annotations

Number of structural domains19
Mean domain length (aa)342 ± 86 aa
Standard deviation of domain lengths85.96
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score74.85
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.57
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)22.41
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A175WCR2 12-372 DESRYADVLGAKKHMNFETARCLSRYLLGEEFAGKWYYCSDEKSKNPRLDSVIQGLGCEGVELTNMYWAILRRYKLIRTAEEEERRR…
A0A1Q5U0Q9 72-365 RQVRQIWEEALREKEDTVLPLLTTNTIRDSLGKRPARLPDTLWQMLRAHCPIRTVEEEQQKQFKEAKPCIVPDTTFARAVDRALRAC…
A0A6A5UDA5 238-781 None
A0A1L9RD86 291-672 None
A0A6A5VPX7 82-580 None
A0A395HH48 4-267 None
A0A6M7YU40 543-875 None
A0A319DKD5 4-334 None
Q2U1J9 2-261 None
A0A2V5IQM4 401-718 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.