DPCstruct | MC36376

Metacluster Properties and Pfam Annotations

Number of structural domains178
Mean domain length (aa)151 ± 36 aa
Standard deviation of domain lengths35.51
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score81.92
Mean fraction of residues predicted as intrinsically disordered0.42
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)25.44
Pfam Score98.94
Assigned Pfam label(s) CL0015- CL0588- CL0530

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1F3XV11 1-155 MQLNNIKAHPGATKSKKRLGRGSGSGHGVTSGKGDKGQLARSGGSVRPGFEGGQMPLYRRVPKRGFNNFARRITAIVNIGDLDTFDF…
W0TG22 156-352 SFVRHISILSSLKPSEGSIKGYKRLGRGPSSGKGKTSGRGQKGQKARGHVKSWFEGGQTPIYKLFPKLGFTNVTSLDLKELNLERIK…
A0A3Q2KWU4 7-111 None
A0A7S4CTY7 163-338 None
A0A2N2GZB5 2-151 None
A0A822XZI2 74-193 None
A0A556TYQ8 18-210 None
A0A2P6NX82 55-234 None
F8FA28 1-85 None
A0A654H4J0 7-140 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.