DPCstruct | MC36371

Metacluster Properties and Pfam Annotations

Number of structural domains438
Mean domain length (aa)171 ± 43 aa
Standard deviation of domain lengths42.54
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score82.91
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.45
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)27.62
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1H3HVF5 96-344 NTDFVVTGYKNRYGDLRAAFGNDLEKYYRHYLDYGVDEKRDGSACDTVQNPITKYKGIDYKLVYNYATYKGNYEDLAKAFKDDDVAY…
A0A327M9D2 23-172 QNPDVAQAGINPLQHFLDYGRSEGRAAHAAVGFDIRGGFDSEYYLLTNPTVGNAGMDALQHWHAYGWQAGVNPNYLFDTKYYLAQNP…
A0A6M1LVY5 140-347 None
A0A7B7BWR2 122-290 None
A0A538PWJ3 338-533 None
A0A7W5Z4I3 401-594 None
A0A2S7J9M3 57-239 None
A0A5E8H1Q8 507-668 None
A0A5E8H064 9-172 None
A0A3A1P400 27-135 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.