DPCstruct | MC36357

Metacluster Properties and Pfam Annotations

Number of structural domains490
Mean domain length (aa)323 ± 76 aa
Standard deviation of domain lengths76.43
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score79.47
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.47
Mean intra-cluster local Distance Difference Test score0.49
Mean intra-cluster sequence similarity (%)16.28
Pfam Score94.09
Assigned Pfam label(s) CL0552- PF05699- CL0012- CL0016- CL0072

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4W5MLS4 64-358 YVRDFKAKVQYFRFWCQVGLMPSEFEWLNRYFVFMHIKITVTRKTLFEDSFQQIMSFNAQDLRRRLWIIFPGEEGLDYGGVAREWFF…
A0A1A8LH26 3-306 RASICRIKVVDDLLAVFTDSSIMNVTLKMDFVNEKAIDDAGVSREVYTAFWEQVLEQCEGEMERVPRLRPDFSEAEWQAVGRIWVKG…
A0A7M5UUV6 338-678 None
A0A4S8N003 604-1030 None
K3WX59 431-732 None
G0P4C2 613-1081 None
A0A7J6D7Y1 214-458 None
A0A7J6D563 36-412 None
A0A6A6L1E4 215-496 None
A0A812KH71 115-513 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.