DPCstruct | MC36339

Metacluster Properties and Pfam Annotations

Number of structural domains456
Mean domain length (aa)208 ± 42 aa
Standard deviation of domain lengths42.01
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score82.24
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)16.48
Pfam Score98.89
Assigned Pfam label(s) CL0023- CL0020- CL0182- CL0582

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7Y2VCM3 134-323 KSYIALFALVLMITLLVFNIVPGAVAALIAAGIILITQCVPLTKAYKGISWISVIMIAAMIPMGIALQKTGTATMIANGLVNSLGAL…
A0A6I3J6Z5 100-355 FAFATLWLANGASLLLPISNLTNLLAVERTGQSAGAFVADLWLPQLVVLAVVVAVLALRHRAALAGTYVVPRTRPSYDAVLVAGGAL…
A0A6T7IR04 81-311 None
A0A1U7VYP7 126-341 None
A0A7T1HYH1 51-269 None
A0A7G8T7P7 60-272 None
A0A1V5ZQX9 66-424 None
A0A7S2RJ39 542-742 None
A0A1X6PK08 762-1010 None
A0A2U8G2P1 232-443 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.