DPCstruct | MC36237

Metacluster Properties and Pfam Annotations

Number of structural domains37
Mean domain length (aa)340 ± 87 aa
Standard deviation of domain lengths86.83
Length coefficient of variation0.26
Mean AlphaFold2 pLDDT confidence score81.72
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)21.82
Pfam Score94.74
Assigned Pfam label(s) PF16547- PF07947- PF16507

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0M3I1M1 74-423 NVILEPDYDNRFVHKACSILKTLCINVVLRREDLTLPWRPVYELYKETVYGRNEKCIDKTILRETILCIKKLFPLPATREILQEIRP…
Q5A2T3 264-650 LRVNLARVYYAICLCRGQHVNLKTYIRIFELLTKDQLLLYSHGLRLPWEDLCRELELHFAPIDAGLTIFEKKDHKQLIKLASRANYF…
V5DQ01 133-491 None
A0A553N0R4 91-379 None
A0A3Q0JH44 95-483 None
A0A820AE08 2-253 None
A0A0D8XVV1 152-490 None
A0A183MWF2 77-444 None
A0A814KRI4 12-414 None
C1GVY2 591-1023 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.