DPCstruct | MC3621

Metacluster Properties and Pfam Annotations

Number of structural domains106
Mean domain length (aa)149 ± 25 aa
Standard deviation of domain lengths25.49
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score87.65
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)38.31
Pfam Score98.21
Assigned Pfam label(s) CL0023- CL0036- CL0123

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6C0INI8 11-140 VGLQHGDEGKGKVAHALLNQNDYDYCIRYNGGPNAGHTIQLSHEKSITLHQLPCGVLNKVPSIIGTNCVIDLTRLEAEINEVECALP…
A0A0B8PU01 4-151 VIGNGVVLSPEALLKEMKPLEERGIPVRERLFVSEACPLILPYHIAVDQAREIARGKKAIGTTGRGIGPAYEDKVARRGLRVGDLFD…
A0A7F8K8H2 26-173 None
A0A6J0TWQ5 44-220 None
A0A3L7Y5V8 136-335 None
A0A7U3BV29 1-118 None
A0A424NSH0 1-176 None
A0A669CGU4 22-132 None
A0A816QG99 14-133 None
A0A2A2K597 2-147 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.