DPCstruct | MC36209

Metacluster Properties and Pfam Annotations

Number of structural domains24
Mean domain length (aa)119 ± 3 aa
Standard deviation of domain lengths2.93
Length coefficient of variation0.02
Mean AlphaFold2 pLDDT confidence score91.29
Mean fraction of residues predicted as intrinsically disordered0.16
Mean length-normalized TM-Score0.94
Mean intra-cluster local Distance Difference Test score0.93
Mean intra-cluster sequence similarity (%)47.88
Pfam Score100.00
Assigned Pfam label(s) CL0125

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
W2IBD5 1-120 MSLEEAAQTFYGLEEYPWNAAAKSIVYVKSRLSWIFETYTDGGLVSSGQVDQFTTGAYYTYLLEMDDDGTIIGGEWVYKSDDDHPDF…
W2HTE0 1-120 MPPEKASQIFYGLQETPWNHDFKRIKNIKSRLSWINERYSDGGVVASDLIENFTVRVDYDYILELDECDNIIGGEWLYESNNNHPDF…
A0A225VE89 173-292 None
W2YJI0 645-764 None
A0A6A3N6Q0 215-332 None
K3WTJ2 272-392 None
A0A5D6XSX4 193-312 None
A0A5D6XPY7 133-254 None
A0A6A3JMH2 96-208 None
A0A6A3KNS2 329-441 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.