DPCstruct | MC36194

Metacluster Properties and Pfam Annotations

Number of structural domains363
Mean domain length (aa)134 ± 23 aa
Standard deviation of domain lengths23.11
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score89.06
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.72
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)25.67
Pfam Score99.75
Assigned Pfam label(s) CL0254- PF01425

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1F7LJW9 8-145 TAVEARRLIGARGLSPVELVESCIGRIEQWNPHVNAVVTTCYDRARAEARAAEAAVMRGEALPPLHGLPVGIKDLDETEGVRTTYGS…
K9IEG3 13-148 QKLVDRELTVTELVSQTLDQIEADQAVLNDFVTINRDEALKQAQAIDEKGVDPDNLWAGIPIAVKDNIVTKGLKTTASSKMLSNFTP…
A0A5P1F3N3 149-285 None
G0RRP1 255-381 None
A0A820L6H4 9-97 None
A0A535W2U2 2-119 None
A0A0D2Y6F9 159-277 None
A0A4Z1IQA5 108-221 None
A0A7W3JPW0 8-129 None
A0A2R6QQ54 81-221 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.