DPCstruct | MC36149

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)186 ± 13 aa
Standard deviation of domain lengths12.81
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score95.39
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.92
Mean intra-cluster local Distance Difference Test score0.86
Mean intra-cluster sequence similarity (%)48.21
Pfam Score100.00
Assigned Pfam label(s) PF00374

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A447PAT6 19-208 IRNIMLATLWCHDHLVHFYQLAGMDWIDVLNALKANPRATSQLAQSLSAWPMSSPGYFFDVQNRLKKFVDGGQLGIFRNGYWGHPQY…
A0A6N6X8R0 2-193 IRNIILAAHTTHDHIVHFYQLSALDWVDITSALKADPAKASAMLNGVSSWHLNSAEEFTKVQNKIKDLVASGQLGIFANGCWGHPAM…
A0A1X7AAA4 40-236 None
A0A1W1WVN2 93-277 None
A0A379VPS7 1-203 None
H6SN26 105-293 None
A0A101G1N1 90-258 None
A0A1G6CA24 12-197 None
A0A1B6NQE5 143-334 None
A0A2Z6TKL4 474-660 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.